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Table 2 Transplantation outcomes: engraftment and acute graft versus host disease

From: Non-T-depleted haploidentical transplantation with post-transplant cyclophosphamide in patients with secondary versus de novo AML in first complete remission: a study from the ALWP/EBMT

 

Overall (n = 1711)

de novo (n = 1480)

sAML (n = 231)

P

Engraftment HSCT

    

Graft failure

82 (5%)

70 (4.9%)

12 (5.6%)

0.69

Engrafted

1558 (95%)

1354 (95.1%)

204 (94.4%)

 

Mssing

71

56

15

 

cumulative incidence of PMN > 500, day 30

91.1% [89.5–92.4]

86.6% [81.2–90.5]

0.037

Acute GVHD

    

Grade I

285 (17.4%)

249 (17.5%)

36 (16.7%)

Not done

Grade II

303 (18.5%)

255 (18%)

48 (22.3%)

 

Grade III

103 (6.3%)

93 (6.5%)

10 (4.7%)

 

Grade IV

38 (2.3%)

34 (2.4%)

4 (1.9%)

 

Present, grade unknown

23 (1.4%)

21 (1.5%)

2 (0.9%)

 

No aGvHD present (Grade 0)

883 (54%)

768 (54.1%)

115 (53.5%)

 

Missing

76

60

16

 
  1. sAML secondary acute myeloid leukemia, HSCT hematopoietic stem cell transplantation, GVHD graft-versus-host disease, a acute, PMN polymorphonuclear cells