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Table 1 Clinical and pathologic characteristics of breast tumors by Amplicon class

From: Topoisomerase II alpha gene copy loss has adverse prognostic significance in ERBB2-amplified breast cancer: a retrospective study of paraffin-embedded tumor specimens and medical charts

Tumor Properties

Amplicon Class, number of patients

 
  

Class I

Class II

Class III

Class IV

p-value

Invasion

present

14

12

14

14

0.913

 

DCIS only

2

3

2

2

 

Type (invasive)

Ductal

12

12

14

14

0.115

 

Lobular

2

0

0

0

 

Grade (invasive)

II

5

2

1

4

0.146

 

III

9

10

13

10

 

Clinical Stage

I

5

6

6

4

0.336

 

II

4

5

5

5

 
 

III

2

2

1

5

 
 

IV

3

0

1

0

 

Age

under 50

6

6

7

9

0.720

 

over 50

10

9

9

7

 

Hormone receptors

ER+/PR+

4

3

3

3

0.710

 

ER+/PR-

4

2

5

3

 
 

ER-/PR+

2

1

0

0

 
 

ER-/Pr-

4

6

6

8

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