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Figure 1 | Journal of Hematology & Oncology

Figure 1

From: Low-level expression of HER2 and CK19 in normal peripheral blood mononuclear cells: relevance for detection of circulating tumor cells

Figure 1

Detection of Cytokeratin 19 (CK19) by LCx in metastatic breast cancer patients. Semi-quantitative RT-PCR for CK19 and Beta2 microglobulin (B2M) was performed on PBMC after BerEP4 immunomagnetic selection for malignant epithelial cells from 10 patients with untreated metastatic breast cancer. CK19 assays were run in duplicate on two separate occasions with the average from each sample shown using error bars. B2M assays were run once per sample as previous experiments have shown the CV of duplicates to be <2%. The change in fluorescent energy serves as the reported value expressed in counts/sec/sec (c/s/s).

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