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Figure 4 | Journal of Hematology & Oncology

Figure 4

From: Rosai dorfman disease of the orbit

Figure 4

Histopathologic section showing a polymorphous population of cells consisting of mature lymphocytes and plasma cells interspersed with histiocytes. Histiocytes are large with a vesicular nuclei and abundant cytoplasm with engulfed lymphocytes and plasma cells, a phenomenon called lymphophagocytosis or emperipolesis, a hallmark of Rosai-Dorfman disease (arrow) (× 500, hematoxylin, eosin). Published with permission from Elsevier. This figure was published in the Clinical Ophthalmic Oncology, Vemuganti GK, Honavar SH, Eyelid Stroma Tumors, Page 105, Copyright Elsevier 2007.

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