ALK-positive diffuse large B-cell lymphoma: report of four cases and review of the literature

Table 1 Clinical characteristics of the reported cases

Case	Age	Sex	Primary site	Bone marrow involvement	Stage	IPI	Therapy	Survival (Months)	Outcome
1	27	M	Bone	Yes	IVB	3	HyperCVAD	11	Alive, with disease
2	41	F	Nasal fossa	No	IA	0	Radiotherapy	13	Alive, NED
3	13	F	Cervical LN	No	IIB	2	LNH96-2002	62	Alive, NED
4	70	M	Cervical LN	No	IIIB	3	CHOP	72	Alive, NED

IPI – International Prognostic Index.
NED – no evidence of disease.
LN – lymph node.
HyperCVAD – hyperfractionated cyclophosphamide, vincristine, doxorubicin and dexamethasone alternating with cytarabine and methotrexate.
CHOP – cyclophosphamide, doxorubicin, vincristine, prednisone.

ISSN: 1756-8722