Figure 1

Typical 2-DE serum protein profiles of negative control women and patients in different stages of EOCa. Unfractionated serum samples of patients and negative controls were subjected to 2-DE and silver staining. Panel A demonstrates a typical representative 2-DE serum protein profile of negative control women. Panels B, C, D and E demonstrate typical representative unfractionated serum protein profiles of the patients with EOCa in stages I, II, III and IV, respectively. For all panels, the acidic sides of the 2-DE gels are to the left and relative molecular mass declines from the top.