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Table 2 Observations during sepsis, severe sepsis and septic shock in the immunocompromised cohort as compared to observations during recovery

From: Plasma protein C levels in immunocompromised septic patients are significantly lower than immunocompetent septic patients: a prospective cohort study

Variables

Immuno-compromised 'Non Sepsis'

Immuno-compromised 'Sepsis'

Immuno-compromised 'Severe sepsis'

Immuno-compromised 'Septic shock'

Immuno-compromised 'Recovery'

'n'

6

7

11

2

13

Age (Range)

59 (29-74)

62 (45-81)

64 (57- 74)

64

59.5 (33- 81)

Protein C level in μg/ml (CL*)

3.96

(2.51- 5.41)

2.59

(1.98-3.21)

p§- 0.031

2.27

(1.63- 2.9)

p§- 0.0011

1.23

3.82

(3.23- 4.40)

SOFA score (CL*)

2.3

(0.6- 4.1)

2.9

(0.9- 4.7)

p§- 0.94

4.6

(3.5- 5.6)

p§- 0.024

12.5

2.4

(1.4- 3.4)

APACHE II score (CL*)

13.2

(9.8- 16.6)

14.6

(13.5- 15.6) p§- 0.233

17.6

(15.7- 19.6) p§- 0.0004

28

11.8

(9.8- 13.8)

Fibrinogen level in g/l (CL*)

2.94

(2.15- 3.73)

5.41

(3.34- 7.49)

p§- 0.68

5.54

(3.63- 7.45)

p§- 0.51

8.65

4.26

(3.53- 4.98)

WBC (× 10 9 /l)

1.16

4.94

0.5

0.9

4.7

Platelets (× 10 9 /l)

61.8

88.3

21.5

77.5

83

  1. * Confidence limits (in brackets)
  2. § p- p Value obtained when variables during different septic categories were compared to observations during recovery. There was no statistical difference among the variables (Protein C, APACHE II & SOFA scores) measured during non-sepsis and recovery.
  3. p values for the septic shock cohort have not been provided because of the small sample numbers.