From: The transplant iron score as a predictor of stem cell transplant survival
Potential Risk Factors | Covariables | Hazard Ratio | 95% CI | p-value |
---|---|---|---|---|
Iron Overload | Iron Score (0-3) | 1.8 | 1.1 to 2.7 | 0.01 |
BMT Risk Factors | ||||
Age | <40, 40s, 50s, 60s | 1.5 | 0.9 to 2.3 | 0.08 |
Gender | Male | 0.8 | 0.4 to 1.6 | 0.54 |
Donor-Type | Auto, Sibling, MURD | 1.6 | 0.9 to 2.7 | 0.06 |
Remission Status | CR1, CR2, No remission | 1.1 | 0.7 to 1.7 | 0.70 |
End-Organ Damage | ||||
Heart Damage | Ejection Fraction | 1.4 | 1.0 to 1.9 | 0.03 |
Liver synthetic function | INR | 1.3 | 0.9 to 1.9 | 0.10 |
Hepatocellular damage | AST + ALT | 0.8 | 0.6 to 1.2 | 0.32 |
Liver obstruction | Total Bilirubin | 0.8 | 0.6 to 1.1 | 0.25 |
Inflammation | C-reactive protein | 1.0 | 0.7 to 1.4 | 0.97 |