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Figure 1 | Journal of Hematology & Oncology

Figure 1

From: Genomic profiling of plasmablastic lymphoma using array comparative genomic hybridization (aCGH): revealing significant overlapping genomic lesions with diffuse large B-cell lymphoma

Figure 1

Plasmablastic lymphoma (PL) is more similar to diffuse large B-cell lymphoma (DLBCL) and AIDS-related DLBCL (AIDS-DLBCL) than plasma cell myeloma (PCM). A. Upper panel: The heatmap of genomic lesions by array CGH among 4 groups of lymphoma studied. The left column shows the number of chromosomes. The right column shows the frequencies of gains (represented by positive values) or loss (represented by negative values). Lower panel: The Pearson correlation coefficient among different groups of lymphomas. B. FISH validation of gains of 16p13.3 frequently identified in PL cases by array CGH. Shown is the interphase cells hybridized with RP11-88L24 (2q31.2/Red) as control and RP11-417B20 (16p31.2/Green) in a representative case. A magnified image of an interphase cell showing three copies of RP11-417B20 and two copies of RP11-88L24 is shown as an inset.

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Journal of Hematology & Oncology

ISSN: 1756-8722

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