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Table 2 Summary table showing the hazard ratios from Cox regression analyses for the three IPI models, baseline IPI, rIPI1 and rIPI2

From: Routine use of ancillary investigations in staging diffuse large B-cell lymphoma improves the International Prognostic Index (IPI)

 

rIPI1#

Hazard ratios

(95% CI)

Baseline IPI

Hazard ratios

(95% CI)

rIPI2

Hazard ratios

(95% CI)

Low-risk IPI

(score 0/1)

Reference

Reference

Reference

Low-intermediate IPI

(score 2)

2.0 (0.61, 6.76)

p = 0.248

1.56 (0.54, 4.51)

P = 0.4

1.8 (0.5, 6.0)

P = 0.3

High-intermediate IPI

(score 3)

7.6 (2.61, 22.36)

p < 0.0001

5.32 (2.14, 13.22)

P < 0.0001

6.4 (2.2, 18.6)

P = 0.001

High-risk IPI

(score 4/5)

8.9 (2.94, 27.17)

p < 0.0001

6.9 (2.61, 18.32)

P < 0.0001

8.1 (2.7, 24.6)

P < 0.001

  1. #Cox regression using forward likelihood ratio method (X2: 31.5, df = 3, p < 0.0001)
  2. Cox regression entering baseline IPI into the model first (X2: 27.4, df = 3, p < 0.0001)
  3. Cox regression entering rIPI2 in to the model first (X2: 28.2, df = 3, p < 0.0001)