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Table 2 Probability of engraftment and growth of human ALL and AML blasts in SCID mice by subcutaneous inoculation

From: Autonomous growth potential of leukemia blast cells is associated with poor prognosis in human acute leukemias

Leukemias

No.

Engraftment & Growth (%)

p-value

ALL

67

30 (44.8%)

 

   B-lineage-ALL

56

25 (44.6%)

 

new

22

5 (22.7%)

 

rel/ref

34

20 (58.8%)

p < 0.05

   T-ALL

11

5 (45.5%)

 

new

5

0 (0%)

 

rel/ref

6

5 (83.3%)

p < 0.01

AML

66

29 (43.9%)

 

new

35

9 (25.7%)

 

rel/ref

31

20 (64.5%)

p < 0.01

  1. new = newly diagnosis; rel/ref = relapse/refractory