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Table 3 Characteristics of the leukemia cell lines established in long-term in vitro cultures

From: Autonomous growth potential of leukemia blast cells is associated with poor prognosis in human acute leukemias

Leukemia cell lines

Classifications

Clinical Status

Survival*

(months)

Kayotypes

BA25**

B-ALL (L3)

Relapse-1/refractory

1.3

45, xy, t(2;8)(p12;q24),-4,+7,-10, idemx2; 44-47, t(2:8)(p23, q24)

BA78**

B-ALL (L3)

Relapse-1/refractory

0.4

45-47, XY, t(8;14)(q24, q32),-16 +1

BA91

B-ALL (L3)

relapse-1

4.5

45-46, XY, t(8;14)(q24, q32),

-9, t(11;18)(q13;p11), +14, -16,

+mar1, +mar2, +mar3

BA127

Pre-B-ALL (L1)

relapse-2

0.8

nd

TA7**

T-ALL (L1)

relapse-1

6.0

46, XY

TA27

T-ALL (L1)

relapse-1/refractory

3.0

46, XY

TA83

T-ALL (L1)

relapse-2/refractory

1.5

46, XY, del(9)(p21), -7,

t(11;14)(p13;q11.2) -7

MA120**

AML (M2)

relapse-2/refractory

2.5

46, XY, del (16)(q13q22),

dup(1) (q44q25)

MA126

AML (M4)

secondary leukemia

1.1

46, XY, t(9;11)(p21, q23)

  1. *Survival of patients after leukemia specimens had be taken; nd: not done.
  2. ** Cell lines established from leukemic nodules in SCID mice. The primary specimen did not grow.