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Figure 1 | Journal of Hematology & Oncology

Figure 1

From: Evolution of T-cell clonality in a patient with Ph-negative acute lymphocytic leukemia occurring after interferon and imatinib therapy for Ph-positive chronic myeloid leukemia

Figure 1

The results of FISH and RT-PCR analyses of marrow samples aspirated during different disease stage in a patient with CML. CP-CML, the sample from chronic phase (October 2000); ALL, from the disease stage of acute lymphoblastic leukemia (October 2006); Post-CT, from post-induction chemotherapy for ALL (December 2006). + ve, BCR/ABL positive; - ve, BCR/ABL negative. (a) FISH analysis; (b) RT-PCR analysis. Lane M, 100 bp molecular weight ladder; Lane K, K562 200 bp b3/a2 BCR/ABL positive control; Lane C: negative control; Lane CP-CML, 200 bp b3/a2 products; Lane ALL and Post-CT, BCR/ABL negative.

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