Table 2 Hazard Ratio for Progression Free Survival in biomarkers subgroups in Saturn study.

EGFR IHC positive

0.69 (0.58-0.82)

< .0001

EGFR IHC negative

0.77 (0.51-1.14)

0.1768

EGFR positive by FISH

0.68 (0.51-0.90)

0.0068

EGFR negative by FISH

0.81 (0.62-1.07)

0.1300

EGFR mutation

0.10 (0.04-0.25)

< 0.0001

EGFR wild type

0.78 (0.63-0.96)

0.0185

KRAS mutation

0.77 (0.50-1.19)

0.2246

KRAS wild type

0.70 (0.57-0.87)

0.0009