Figure 2From: Cytostatic and anti-angiogenic effects of temsirolimus in refractory mantle cell lymphomaImmunohistostainings and histological analysis of the lymph node biopsies before and six months after temsirolimus. Quantitative studies showed a significant decrease of cyclin D1, cell proliferation, microvessel density and VEGF-A expression as well as a significant increase in fibrosis after six months of temsirolimus. Cleaved caspase-3 positive cell counts remained unchanged. Bar, 50 μm. * P < 0.05, ** P < 0.01Back to article page