Figure 3From: The anti-myeloma activity of a novel purine scaffold HSP90 inhibitor PU-H71 is via inhibition of both HSP90A and HSP90B1Effect of PU-H71 on the unfolded protein response (UPR) and apoptosis. (A) Immunoblot of XBP1 s on 24 hour treated RPMI-8226/DOX40 cells. (B) Immunoblot on 24-hour treated MM.1R cell lysate for cleaved caspase 3 and cleaved PARP (cPARP).Back to article page