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Table 2 Genes/GAPDH ratio at the mRNA level (The densitometric data are presented as fold changes as compared with their corresponding controls)

From: Lobaplatin arrests cell cycle progression in human hepatocellular carcinoma cells

Treatment time

cyclin B

cyclin D1

CDK1

CDK4

CDK6

CDC25C

P53

p16

p21

p27

0 h

1

1

1

1

1

1

1

1

1

1

12 h

0.89

1.47

0.83

1.21

1.10

0.51

3.03

1.22

2.05

1.26

24 h

0.53

1.36

0.53

0.95

1.14

0.54

2.69

1.85

2.50

1.32

36 h

0.18

0.87

0.25

0.52

1.18

0.21

1.30

1.59

3.14

2.05

48 h

0.09

0.59

0.13

0.53

1.04

0.12

0.79

1.77

3.64

1.95