Table 3 Genes/GAPDH ratio at the protein level (The densitometric data are presented as fold changes as compared with their corresponding controls)
From: Lobaplatin arrests cell cycle progression in human hepatocellular carcinoma cells
Treatment time | cyclin B | cyclin D1 | CDK1 | pCDK1 | CDK4 | pCDK4 | CDK6 | CDC25C | p53 | p16 | p21 | p27 | E2F | Rb | pRb |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
0 h | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
12 h | 0.94 | 1.17 | 0.79 | 1.50 | 1.15 | 0.75 | 1.21 | 1.25 | 4.16 | 0.87 | 2.15 | 1.58 | 1.14 | 0.98 | 1.01 |
24 h | 0.47 | 1.28 | 0.59 | 0.39 | 0.95 | 0.51 | 1.04 | 1.58 | 2.41 | 1.66 | 5.32 | 2.04 | 0.81 | 0.39 | 0.55 |
36 h | 0.26 | 0.77 | 0.23 | 0.15 | 0.56 | 0.36 | 1.11 | 0.63 | 1.57 | 1.39 | 7.00 | 3.00 | 0.46 | 0.45 | 0.29 |
48 h | 0.07 | 0.64 | 0.09 | 0.02 | 0.65 | 0.19 | 1.19 | 0.47 | 0.63 | 1.74 | 5.63 | 1.96 | 0.40 | 0.39 | 0.34 |