Figure 3From: Reactivating aberrantly hypermethylated p15 gene in leukemic T cells by a phenylhexyl isothiocyanate mediated inter-active mechanism on DNA and chromatinPHI induced histone acetylation and acetyltransferase up-regulation. A: The acetylation of histone H3 and H4 was significantly increased in a concentration and time-dependent manner by PHI. B: PHI up-regulated the expression of acetyltransferase P300/CBP in a concentration and time-dependent manner.Back to article page