Table 1 Clinical studies of MS-275 (SNDX-275)

I

Relapsed or refractory AML (39).

Once weekly for 4 weeks of a 6 week cycle

8 mg/m²

[92]

I

Refractory solid tumors and lymphoid(22)

Once weekly for 4 weeks of a 6 week cycle

6 mg/m²

[90]

I

Refractory solid tumors and lymphoid(27)

Once weekly for 3 weeks of a 4 week cycle or once every other week.

4 mg/m²

[91]

I

Refractory solid tumors and lymphoid

Once every 2 week of 6 week cycle.

10 mg/m²

[89]