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Table 2 Canfosfamide and pegylated liposomal doxorubicin treatment administration and adjunctive care (N = 39)

From: Phase 2 study of canfosfamide in combination with pegylated liposomal doxorubicin in platinum and paclitaxel refractory or resistant epithelial ovarian cancer

Dosing (Total # of Cycles = 245)

Canfosfamide

PLD

Median # Cycles/Patient (range)

4.0 (1-18.0)

Median Cumulative Dose, mg/m2 (range)

3840 (960.0-13978)

200.3 (50.0-726.4)

Dose Reductions

28

31

Dose Interruptions

14

6

Adjunctive Treatment

# Cycles

% Cycles

Granulocyte Growth Factor Support

79

32.2

Erythropoietin Support

49

20.0

RBC Transfusions

18

7.3

Platelet Transfusions

1

0.4