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Table 3 Determination of the level of XPC gene 5' regulatory region DNA co-precipitated with the transcription factors CREB1 and Sp1 by IP in both untreated and VPA-treated HTB4 and HTB9 bladder cancer cells a.

From: Histone deacetylases (HDACs) in XPC gene silencing and bladder cancer

IP antigen

HTB4

HTB9

 

No treatment

VPA treatment

No treatment

VPA treatment

CREB1

1

4.6 ± 0.4

1

2.2 ± 0.2

Sp1

1

2.2 ± 0.3

1

2.0 ± 0.3

  1. a The level of XPC gene 5' regulatory region DNA co-precipitated in the untreated cells was counted as 1 and the level of XPC gene 5' regulatory region DNA co-precipitated in the VPA-treated cells was calculated as fold change to that of the untreated cells for each cell line. The fold change was expressed as Mean ± S.D. The results were from three independent IP experiments.