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Figure 3 | Journal of Hematology & Oncology

Figure 3

From: Retinoic acid induces HL-60 cell differentiation via the upregulation of miR-663

Figure 3

ATRA treatment significantly upregulates miR-663 in HL-60 cells. (A) TaqMan qRT-PCR miRNA assays were used to quantify the time course of mature miR-663 expression in HL-60 cells treated with ATRA. Expression was normalized to endogenous U6 expression. (B) Summary of TaqMan qRT-PCR miRNA assay results showing miR-663 was significantly upregulated in ATRA treated cells. At 72 h, mir-633 expression in ATRA treated cells (6.93 ± 1.31) was significantly increased compared to cells treated with 1% ethanol (1.17 ± 0.24, p < 0.01).

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