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Table 2 Multivariate analyses of numbers of LNs obtained and recurrence of colon cancer at 2 and 5 years

From: Evaluation of lymph node numbers for adequate staging of Stage II and III colon cancer

 

Adjusted a HRs (95% C.I.)

LNs extracted

Stage II

Stage III

Recurrence in 2 years

  

Current guideline

  

< 12

ref

ref

≥ 12

0.62 (0.32, 1.22)

1.27 (0.67, 2.40)

Quartiles

  

1-6

ref

ref

7-11

0.72 (0.29, 1.79)

1.49 (0.52, 4.26)

12-19

0.63 (0.26, 1.52)

1.54 (0.55, 4.34)

≥ 20

0.33 (0.12, 0.91)

1.59 (0.54, 4.64)

Recurrence in 5 years

  

Current guideline

  

< 12

ref

ref

≥ 12

0.67 (0.37, 1.24)

1.16 (0.67, 1.99)

Quartiles

  

1-6

ref

ref

7-11

0.64 (0.27, 1.51)

1.24 (0.53, 2.91)

12-19

0.62 (0.26, 1.52)

1.23 (0.53, 2.84)

≥ 20

0.47 (0.20, 1.11)

1.44 (0.61, 3.42)

  1. HR, hazard ratio; CI, confidence interval.
  2. aAdjusted for age, race, and tumor grade. The Stage III model was also adjusted for chemotherapy status and the number of positive LNs.