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Figure 3 | Journal of Hematology & Oncology

Figure 3

From: Acute myeloid leukemia of donor origin after allogeneic stem cell transplantation from a sibling who harbors germline XPD and XRCC3 homozygous polymorphisms

Figure 3

RFLP analysis of DNA generated by digestion of XPA (3A), XPD (3B), XRCC1 (3C), XRCC3 (3D), and RAD51 (3E) PCR products digested with or without their specific RFLP diagnostic restriction enzymes. M = 50 bp ladder marker; Lane 1 = non-digested PCR amplification of normal allele; Lane 2 = digestion pattern from the positive control K562 myeloid cell line alleles; Lane 3 = digestion pattern from patient alleles before transplantation; Lane 4 = digestion pattern from patient alleles from AML cell DNA after transplantation; Lane 5 = digestion pattern from donor cell alleles.

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Journal of Hematology & Oncology

ISSN: 1756-8722

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