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Table 1 Results of JAK2V617F Tests

From: Relevance of JAK2V617F positivity to hematological diseases - survey of samples from a clinical genetics laboratory

Sample Types and Diagnosis

Number of total samples

Number of V617F+ samples

Percentage of V617F+ samples

Average ages of V617F- samples

Average ages of V617F+ samples

Blood and Bone Marrow Specimens

Hematological diseases

665

32

4.8*

52.8

64.6**

Ph- MPNs

18

14

78*

62.3

69.2

Leukocytosis

23

2

8.7*

50.8

62.5

Acute myeloid leukemia

113

6

5.3*

47.9

56.8

Leukemia (unspecified)

70

3

4.3*

47.1

66.6

Anemia

65

2

3.1*

54

76.8

Lymphoma

98

3

3.1*

55.6

60.2

MDS and probable MDS

111

2

1.8

55.8

49.9

Acute lymphoblastic leukemia

21

0

0

13

-

Chronic lymphocytic leukemia

14

0

0

67.4

-

Chronic myeloid leukemia

32

0

0

47.9

-

Multiple myeloma

50

0

0

65.1

-

Thrombocytopenia

29

0

0

60.1

-

Other hematological diseases

21

0

0

54.4

-

Non-hematological diseases

1731

0

0

7.3

-

Developmental disorders

1370

0

0

4.9

-

Multiple miscarriage/infertility

83

0

0

30.2

-

Others

278

0

0

14.8

-

Normal samples

232

0

0

54.5

-

Amniotic Fluid Specimens

Cytogenetic screening

267

0

0

31.3

-

  1. * P < 0.05 when comparing the percentage of JAK2V617F positivity with normal samples.
  2. ** P < 0.05 when comparing the ages of JAK2V617F+ and JAK2V617F- samples within each disease.