Skip to main content

Table 2 Chromosomal Abnormalities in MPN and JAK2V617F-Positive Samples

From: Relevance of JAK2V617F positivity to hematological diseases - survey of samples from a clinical genetics laboratory

Diagnosis Cases V617F Chromosomal Abnormalities
Ph-MPNs 1 + Monosomy 20
  1 + Loss of chromosome Y
  1 + Isochromosome of the entire long arm of chromosome 8
  1 - Loss of chromosome Y
  1 - Chromosomes 9 and 12 translocation at 9p21 and 12p12
Leukocytosis 1 + Deletion of the long arm of chromosome 16 at 16q23
AML 1 + Chromosomes 8 and 21 translocation 8q22 and 21q22
  2 + 5q deletion and monosomy 7
  1 + Deletion of the long arm of chromosome 5 at 5q21, deletion of the short arm of chromosome 6 at 6p21.3, and monosomy 9
Leukemia (unspecified) 1 + Trisomy 8
  1 + Trisomy 20
Anemia 1 + Trisomy 8
MDS 1 + Deletion of the long arm of chromosome 5 at breakpoint 5q31