| Number tested | Mean adjusted IQ* (SD) | Difference in means (95% CI) | t-test p-value | ||
---|---|---|---|---|---|---|
 | Controls |    Patients |    Controls | Patients |  |  |
FSIQ | Â | Â | Â | Â | Â | Â |
   5 months |    157 |    284 | 102.5 (14) | 101.0 (15) | 1.4 (-1.5 : 4.4) |    0.3 |
   3 years |    173 |    366 | 104.8 (14) | 97.7 (16) | 7.1 (4.4 : 9.8) |    < 0.0001 |
   5 years |    132 |    289 | 105.2 (15) | 100.0 (16) | 5.2 (1.9 : 8.5) |    0.002 |
VIQ | Â | Â | Â | Â | Â | Â |
   5 months |    158 |    287 | 102.0 (14) | 99.6 (15) | 2.3 (-0.5 : 5.2) |    0.1 |
   3 years |    173 |    366 | 103.4 (15) | 97.7 (15) | 5.7 (3.1 : 8.4) |    < 0.0001 |
   5 years |    132 |    289 | 103.2 (14) | 99.6 (15) | 3.6 (0.5 : 6.7) |    0.02 |
PIQ | Â | Â | Â | Â | Â | Â |
   5 months |    160 |    299 | 102.5 (15) | 102.0 (16) | 0.5 (-2.5 : 3.5) |    0.7 |
   3 years |    173 |    368 | 105.5 (15) | 98.2 (16) | 7.3 (4.5 : 10.1) |    < 0.0001 |
   5 years |    132 |    289 | 106.4 (16) | 100.5 (17) | 5.9 (2.5 : 9.3) |    0.0006 |