Time | Management process |
---|---|
d1 (3/20) | Diagnosis established; Induction chemotherapy consisting of homoharringtonine, cytarabine and daunorubicin began. |
d30 | Bone marrow smear showed 20.4% megakaryoblasts and 24.8% promegakaryocytes (chemotherapy failure); Second induction chemotherapy. |
d60 | Bone marrow smear showed 6% megakaryoblasts and 11% promegakaryocytes (partial remission); Imatinib treatment started (600 mg/d) and CAG regimen |
d67 | WBC: 3.5 × 109/L. |
d69 | Imatinib reduced to 400 mg/d. |
d75 | Imatinib discontinued (WBC: 0.9 × 109/L). |
d102 | Imatinib restarted (200 mg/d); WBC: 4.3 × 10 9 /L (d106) |
d107 | Imatinib increased to 400 mg/d d110: complete hematological remission WBC:3.2 × 109/L (d110); 3.5 × 109/L (d120); 4.2 × 109/L (d130) |
d132 | Imatinib discontinued (due to financial reasons) |
d150 | Relapse. |
d177 | Patient deceased. |