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Table 1 IC50 values for each drug were calculated by performing dose response experiments with gefitinib and paclitaxel

From: Molecular mechanism of the schedule-dependent synergistic interaction in EGFR-mutant non-small cell lung cancer cell lines treated with paclitaxel and gefitinib

IC50

Hcc827

PC-9

PC-9/GR

H1650

Paclitaxel

2.27 ± 0.15nM

2.33 ± 0.47nM

2.59 ± 0.62nM

3.29 ± 0.35nM

Gefitinib

16 ± 1.12nM

19 ± 2nM

2.1 ± 0.39 μM

9.37 ± 0.52 μM