Methoxyflavone derivatives modulate the effect of TRAIL-induced apoptosis in human leukemic cell lines

Table 1 IC₅₀ values of five methoxyflavone derivatives (2'-methoxyflavone, 5-methoxyflavone, DMF, TMF and PMF) in U937 and MOLT-4 cells

Methoxyflavone derivatives	IC₅₀ values (μ g/ml)*
	U937 cells	MOLT-4 cells
2'-MF	31.61 ± 0.68	30.11 ± 0.16
5-MF	46.70 ± 1.60	26.39 ± 2.22
DMF	24.56 ± 2.80	48.13 ± 5.12
TMF	12.95 ± 0.48	30.44 ± 0.52
PMF	19.28 ± 0.55	31.16 ± 2.22

*Means and standard deviations are calculated from triplicates of three independent experiments.

ISSN: 1756-8722