From: BCR-ABL1-independent PI3Kinase activation causing imatinib-resistance
 | [3H]-thymidine (SI) | % cells in G1 | ||
---|---|---|---|---|
 | control | rapamycin | control | rapamycin |
TKI-sensitive | Â | Â | Â | |
BV-173 | 1 | 0.3 +/- 0.1 | 63 +/- 4 | 69 +/- 4 |
EM-2 | 1 | 0.5 +/- 0.1 | 61 +/- 2 | 68 +/- 1 |
JURL-MK2 | 1 | 0.6 +/- 0.1 | 73 +/- 1 | 81 +/- 2 |
TKI-resistant | Â | Â | Â | |
KCL-22 | 1 | 0.4 +/- 0 | 60 +/- 5 | 74 +/- 2 |
NALM-1 | 1 | 0.6 +/- 0.1 | 76 +/- 2 | 80 +/- 1 |
SUP-B15 | 1 | 0.5 +/- 0.1 | 66 +/- 1 | 83 +/- 2 |