Figure 1

Bilirubin level during chemotherapy and allogeneic hematopoietic stem cell transplantation. Chronological dates of the treatment courses were indicated. (A). the first cycle of chemotherapy of DA regimen [Daunorubicin 60 mg/d from day 1 to 3, Cytarabine (Ara-C) 200 mg/d from day 1 to 7]. (B). the second cycle of chemotherapy of IA (Idarubicin 10 mg/d from day 1 to 3, Ara-C 200 mg/d from day 1 to 7). (C). the third cycle of chemotherapy of TA regimen (Pirarubicin 40 mg/d from day 1 to 3, Ara-C 200 mg/d from day 1 to 7). (D). allo-HSCT [fludarabine (30 mg/m2/d, on days -6 to -2) and busulfan (3.2 mg/kg/d, on days -6 to -3) for conditioning; Phenytoin for prophylaxis of busulfan's side affect. Tacrolimus; methotrexate and mycophenolate mofetil (0.5 g twice a day on days 0 to +28) for GVHD prophylaxis; Caspofungin for prophylaxis of fungal infections]. Tropisetron was used during the chemotherapy and conditioning. (E). period of acute GVHD [alanine aminotransferase 321 U/L, aspartate aminotransferase 284 U/L, total bilirubin 61.7 umol/L (3.6 mg/dL), and indirect bilirubin 34.1 umol/L (2.0 mg/dL)].