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Table 2 Total arsenic concentrations in PB RBCs, PB plasma and BM plasma collected during the remission induction therapy

From: Speciation of arsenic trioxide metabolites in peripheral blood and bone marrow from an acute promyelocytic leukemia patient

Days after the start of administration -1 3 7 10 14 17 21 28 42 56
Arsenic concentrations (ngAs/g) PB RBCs 11.6 106.2 141.4 149.7 149.4 128.2 142.7 163.6 184.8 53.7
  PB Plasma 5.55 36.6 41.1 42.2 47.6 49.7 53.0 56.6 55.5 18.5
  BM Plasma 7.59 ND ND ND 53.5 ND ND 72.1 88.1 20.4
  1. Blood samples were collected before the treatment start (day -1), and 3, 7, 10, 14, 17, 21, 28, 42, 56 days after the start of administration. The total arsenic concentrations in each clinical sample were determined by ICP-MS as described in "Patient and Methods". ND: no data.