From: Speciation of arsenic trioxide metabolites in peripheral blood and bone marrow from an acute promyelocytic leukemia patient
Days after the start of administration
-1
14
28
42
56
Arsenic concentrations (ngAs/g)
As(V)
0.35
0.54
1.91
2.34
0.17
As(III)
0
3.43
7.47
4.00
0.10
MA(V)
0.80
12.4
13.0
1.63
DMA(V)
0.63
11.5
12.1
15.1
3.21
AB
0.51
3.49
0.50
0.99
1.00