Table 2 Completed clinical trials at present time with MSC expanded in vitro (http: //clinic altrials.gov)
Condition | Patients (N) | MSC source | Delivery route | Phase | Study design | ClinicalTrials.gov identifier |
|---|---|---|---|---|---|---|
Myocardial Ischemia | 31 | Autologous MSC from bone marrow | intramyocardial injections | Phase I/II | Non-randomized, Single group assignment, Open label | NCT00260338 |
Acute Myocardial Infarction | 80 | Autologous MSC from bone marrow | intracoronary injection | Phase II/ III | Randomized, Parallel assignment, Open Label | NCT01392105 |
Ischemic Heart Disease | 48 | MSC from bone marrow | intracoronary injection | Phase I/II | Non-Randomized, Parallel Assignment, Open label | NCT00135850 |
Heart Failure | 10 | Not mentioned | intramyocardial injections | Phase II | Randomized, Parallel Assignment, Double blind (Subject, Caregiver, Investigator) | NCT00927784 |