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Figure 1 | Journal of Hematology & Oncology

Figure 1

From: MiR-424 and miR-155 deregulated expression in cytogenetically normal acute myeloid leukaemia: correlation with NPM1 and FLT3 mutation status

Figure 1

MiR-424 expression in CN-AML and in normal hematopoietic cells. MiRNA expression was measured by qRT-PCR using total RNA extracted from fresh samples. CN-AML were subdivided in 4 groups: wt = FLT3wt and NPM1wt; NPM1+=FLT3wt and NPM1mutA; FLT3+=FLT3-ITD and NPM1wt; NPM1+/FLT3+=FLT3-ITD and NPM1mutA. Calibration was obtained with respect to normal BM. (A) Relative expression of miR-424 obtained normalizing with respect to RNU6B. (B) Relative expression of miR-424 obtained normalizing with respect to RNU54. (C) Mean threshold cycles (Ct) of miR-424 in CN-AML was obtained by qRT-PCR. The ordinate scale is represented with the values in reverse order. The error bar indicates the±SE. (D) p values of each single group of CN-AML compared to normal samples. ns=not significant.

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Journal of Hematology & Oncology

ISSN: 1756-8722

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