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Table 2 Factors impacting post-induction CR/nCR, post-induction VGPR, post-ASCT CR/nCR and post-ASCT VGPR

From: Treatment outcome and prognostic factor analysis in transplant-eligible Chinese myeloma patients receiving bortezomib-based induction regimens including the staged approach, PAD or VTD

 

Post-induction CR/nCR (%)

Post-induction ≥ VGPR (%)

Post-ASCT CR/nCR (%)

Post-ASCT ≥ VGPR (%)

Regimen

 Staged approach

6 (24 %)

14 (56 %)

15 (62.5 %)

19 (79.2 %)

 PAD

13 (41.9 %)

26 (83.9 %)

23 (74.2 %)

29 (93.5 %)

 VTD

15 (42.9 %)

26 (74.3 %)

19 (63.3 %)

27 (90 %)

p-value

0.268

0.064

0.569

0.242

Age*

p-value

0.547

0.698

0.416

0.730

Gender

male

17 (34 %)

34 (68 %)

27 (57.4 %)

40 (85.1 %)

female

17 (41.45 %)

32 (78 %)

30 (78.9 %)

35 (92.1 %)

p-value

0.518

0.349

0.04

0.501

ISS

 I

10 (34.48 %)

19 (65.5 %)

20 (71.4 %)

26 (92.9 %)

 II

8 (44.44 %)

14 (77.8 %)

13 (72.2 %)

16 (88.9 %)

 III

16 (37.21 %)

33 (73.3 %)

24 (63.2 %)

32 (84.2 %)

p-value

0.781

0.513

0.431

0.559

Isotype

 G

8 (20.0 %)

23 (57.5 %)

18 (47.4 %)

33 (86.8 %)

 L

14 (56.0 %)

20 (80 %)

18 (81.8 %)

19 (86.4 %)

 A

7 (46.67 %)

13 (86.7 %)

11 (78.6 %)

13 (92.9 %)

 D

2 (28.57 %)

6 (85.7 %)

6 (85.7 %)

6 (85.7 %)

 NS

3 (75.0 %)

4 (100 %)

4 (100 %)

4 (100 %)

p-value

0.017

 0.065

0.013

0.908

  1. *: p-value refers to the comparison of the mean age of patients achieving or not achieving a response(CR/nCR or ≥ VGPR).