Test features | Parallel test | Serial test | ||
---|---|---|---|---|
hnRNP K ≥7.160 ppm o AFP ≥ 100 ng/mL | hnRNP K ≥7.160 ppm or AFP ≥ 400 ng/mL | hnRNP KL ≥7.160 ppm and op AFP ≥ 100 ng/mL | hnRNP K ≥7.160 ppm and AFP ≥ 400 ng/mL | |
Sensitivity (Sen) | 93.33 % | 93.33 % | 33.33 % | 33.33 % |
Specificity (Spe) | 44.00 % | 32.00 % | 96.00 % | 92.00 % |
False negative rate (FNR) | 0.0667 | 0.0667 | 0.6667 | 0.6667 |
False positive rate (FPR) | 0.5600 | 0.6800 | 0.0400 | 0.0800 |
Youden index | 0.3733 | 0.2533 | 0.2933 | 0.2533 |
Positive predictive value (PPV) | 0.5000 | 0.4516 | 0.8333 | 0.7143 |
Negative predictive value (NPV) | 0.9167 | 0.8889 | 0.7059 | 0.6970 |
Accuracy | 0.6250 | 0.5500 | 0.7250 | 0.7000 |