Table 2 Characteristics of AML patients with a wild type or mutated IDH1

No. of cases

230

20

210

No. of males/females

101/129

5/15

96/114

.058

Age, years

.860^†

   Median (range)

44 (13-86)

42.5 (15-85)

45 (13-86)

Hemoglobin, g/dL

.311^†

   Median (range)

7.8 (1.4 -14.5)

7.4 (2.9 - 10.8)

7.85(1.4-14.5)

WBC count, x10 ⁹ /L

.323^†

   Median (range)

27.7 (0.6 -494.4)

26.9 (1.0 -190.9)

27.7 (0.6 -494.4)

Platelet, x10 ⁹ /L

.923^†

   Median (range)

46 (1.8-965)

56 (16.9 - 386)

45.5 (1.8-965)

Percentage of blasts

.738^†

   Median (range)

70.19 (6.69-95.44)

75.8 (13.3-91.4)

69.77 (6.69-95.44)

Patients (%)

Patients (%)

FAB classification

   M0

3

1 (5)

2 (0.9)

   M1

51

1 (5)

50 (23.8)

   M2

76

13 (65)

63 (30)

   M3

36

5 (25)

31 (15)

   M4

34

0 (0)

34 (16)

   M5

21

0 (0)

21 (10)

   M6

8

0 (0)

8 (3.8)

   M7

1

0 (0)

1 (0.5)

Patients (%)

Patients (%)

Cytogenetics

   Abnormal

   t(15;17)

36

5 (25)

31 (15)

.184

   t(8;21)

20

0 (0)

20 (10)

.149

   inv(16)

3

0 (0)

3 (1)

.760

   trisomy 8

4

1 (5)

3 (1)

.307

   Other trisomies

7

0 (0)

7 (3)

.524

   All others including monosomies, deletions or combination of these

22

2 (10)

20 (10)

.594

   Complex karyotype

8

0 (0)

8 (4)

.477

   Normal

126

11 (55)

115 (55)

.587