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Table 6 Reported frequencies of IDH1 and IDH2 mutations in APL patients worldwide

From: Molecular alterations of isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) metabolic genes and additional genetic mutations in newly diagnosed acute myeloid leukemia patients

Country

No. IDH1m/all cases (%)

No. of IDH1m in APL (%)

No. IDH2m/all cases (%)

No. of IDH2m in APL (%)

ASIA

    

Taiwan

    

Chou W et al.[18]

27/493 (5.5)

0/37 (0)

ND

ND

China

    

Zhang Y et al.[28]

23/365 (6.3)

3/77 (3.9)

ND

ND

Thailand

    

This study

20/230 (8.7)

5/36(13.9)

24/230 (10.4)

6/36 (16.7)

EUROPE

    

Germany

    

Schnittger S et al.[27]

93/1414 (6.6)

2/88 (2.3)

ND

ND

The Netherlands

    

Abbas S et al.[24]

55/893 (6.2)

0/21 (0)

97/893 (10.9)

0/21 (0)

NORTH AMERICA

    

United States

    

Mardis E et al.[5]

16/188 (8.5)

0/16 (0)

ND

ND

Andersson A et al.[29]

5/227 (2.2)

0/7 (0)

3/227 (1.3)

0/7 (0)

  1. ND, not determined