Table 1 Potential cysteines involved in vWF self-association
From: The unfolded von Willebrand factor response in bloodstream: the self-association perspective
Domain region Identified disulfide bond/cysteines in vWF multimers | ||||
|---|---|---|---|---|
D’ domain | 767 ↔ 808 | 776 ↔ 804 | 810 ↔ 821 | |
D3 domain | 867 ↔ 996 | 889 ↔ 1031 | 898 ↔ 993 | 914 ↔ 921 |
1060 ↔ 1084 | 1071 ↔ 1111 | 1089 ↔ 1091 | 1126 ↔ 1130 | |
1149 ↔ 1169 | 1153 ↔ 1165 | 1196 ↔ 1199 | 1234 ↔ 1237 | |
889, 898 | ||||
A domain | 1272 ↔ 1458 (A1) | 1669 ↔ 1670 (A2) | 1686 ↔ 1872 (A3) | |
A3-D4 domain | 1879 ↔ 1904 | 1899 ↔ 1940 | 1927 ↔ 2088 | |
D4 domain | 1950 ↔ 2085 | 1972 ↔ 2123 | 1993 ↔ 2001 | |
C domain | 2724 ↔ 2774 | 2739 ↔ 2788 | 2750 ↔ 2804 | 2754 ↔ 2806 |
2448, 2451 | 2490, 2491 | 2453, 2528 | 2533 | |