Figure 5From: Tanshinone IIA inhibits metastasis after palliative resection of hepatocellular carcinoma and prolongs survival in part via vascular normalizationEffects of Tan IIA on endothelial cells tube formation and TEC surface expression of growth factor receptors. (A, B) Tan IIA enhanced tube formation of HUVECs and human TECs (50×). (C) The percentage of VEGFR1- and PDGFR-positive TECs and the relative fluorescence intensities. Values were higher in the PR + Tan IIA group than NS group. *p<0.05, **p<0.01. (D) Tube formation was enhanced by Tan IIA in vivo, similar to results seen with Tan IIA incubation in vitro; the addition of the VEGFR1/PDGFR inhibitor SU6668 weakened this enhancement effect.Back to article page