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Table 1 Summary of tumor growth, metastasis, and mice’s survival from three animal experiments of HCCLM3

From: Tanshinone IIA inhibits metastasis after palliative resection of hepatocellular carcinoma and prolongs survival in part via vascular normalization

Items IE (1) IE (2) IE (3)
  Sham PR p NS Tan IIA 1 Tan IIA 5 Tan IIA 10 P b PR+NS PR+Tan IIA 10 p
TV/cm3 2.712±1.262 5.990±3.113 .014 3.314±0.948 3.643±1.231 3.045±1.031 2.825±0.959 .268 4.736±1.660 3.339±0.924 .047
LM 7.22±4.71 110.11±28.01 .000a 7.42±3.61 6.25±2.77 4.83±3.01 2.25±2.86 .001 94.56±31.47 13.56±11.33 .000
CTCs 0.240±0.082 0.926±0.223 .000 ND ND ND ND 0.966±0.276 0.283±0.093 .000a
35 d/%  
Survival/d 76.833±1.778 51.500±2.784 .000 87.000±3.804 85.500±3.128 96.000±2.658 102.667±3.201 .002 47.833±3.280 69.000±1.693 .001
  1. a Student’s t-test, equal variances assumed.
  2. b One-way analysis of variance.
  3. Abbreviations: PR, palliative resection; NS, normal saline; CTCs, circulating tumor cells; IE, in vivo experiment; LM, lung metastasis; ND, not done; TV, tumor volume.