Figure 1
From: Alternative expression of TCRζ related genes in patients with chronic myeloid leukemia
TCRζ 3'-UTR PCR amplification in healthy individual and CML samples. Two splice forms, wild type TCRζ 3'-UTR (906 bp) and alternatively spliced TCRζ 3'-UTR (344 bp), could be detected in healthy individuals (lanes 1 and 2), patients with CML-CP (lane 3 and 4) and patients with CML-CR (lane 5). Thirty-five percent of the CML cases contained only the wild type TCRζ 3'-UTR isoform (lane 3). Lane 6 is an 100 bp DNA ladder.