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Table 1 Summary of therapeutic mAbs included in this review

From: A critical review of the role of Fc gamma receptor polymorphisms in the response to monoclonal antibodies in cancer

Generic name

Brand name

Indication

Construct

Isotype

Target

 rituximab

MabThera®/ Rituxan®

CD20+ lymphoma and CLL

chimeric

IgG1

CD20

trastuzumab

Herceptin®

breast cancer; gastric cancer

humanized

IgG1

HER2

 cetuximab

Erbitux®

colorectal cancer; head and neck cancer

chimeric

IgG1

EGFR