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Table 1 Summary of therapeutic mAbs included in this review

From: A critical review of the role of Fc gamma receptor polymorphisms in the response to monoclonal antibodies in cancer

Generic name Brand name Indication Construct Isotype Target
 rituximab MabThera®/ Rituxan® CD20+ lymphoma and CLL chimeric IgG1 CD20
trastuzumab Herceptin® breast cancer; gastric cancer humanized IgG1 HER2
 cetuximab Erbitux® colorectal cancer; head and neck cancer chimeric IgG1 EGFR