Table 5 Sensitivity of the MDASI-MM to change in ECOG PS ( n = 126)

Change in composite scores

 Core subscale

0.07

1.54

1.66

1.62

1.59^b

0.90

 Severity subscale

0.09

1.35

1.52

1.42

1.43^b

0.91

 Interference subscale

0.16

2.63

2.15

2.38

1.99^b

0.74

Change in MDASI-MM items

 Dry mouth

−0.92

3.49

3.44

3.33

4.36^b

1.08

 Fatigue

−0.28

3.11

2.44

2.68

2.72^b

0.85

 Lack of appetite

0.70

3.09

3.85

3.62

3.15^b

0.85

 Nausea

0.68

2.25

3.48

3.60

2.80^b

0.84

 Drowsiness

−0.52

3.92

2.23

2.92

2.75^b

0.74

 Diarrhea

1.15

3.01

3.68

3.67

2.53^b

0.71

 Vomiting

0.40

1.43

1.89

3.10

1.49^c

0.59

 Mouth/throat sores

0.37

2.18

1.86

3.41

1.49^c

0.50

 Pain

−0.48

3.35

1.15

3.09

1.63^c

0.49

 Muscle weakness

0.42

3.29

1.83

2.52

1.41^c

0.47

 Numbness

0.90

2.70

−0.24

2.21

−1.14^c

0.45

 Disturbed sleep

0.02

3.41

1.20

3.21

1.18^c

0.35

 Bone aches

−1.03

3.59

0.13

3.17

1.16^c

0.34

 Shortness of breath

−0.08

2.23

0.68

2.23

0.76

0.34

 Sadness

−0.02

2.00

0.55

2.77

0.57

0.23

 Difficulty paying attention

0.25

1.87

0.65

2.12

0.40

0.20

 Difficulty remembering

0.02

1.78

0.27

1.62

0.25

0.15

 Constipation

−0.50

2.94

−0.20

2.24

0.30

0.11

 Distress

0.52

2.66

0.68

2.97

0.16

0.06

 Rash

0.32

1.58

0.34

2.16

0.02

0.01