Table 2 Organ toxicity according to Bearman’s criteria
| Â | Grade I or II | Grade III or IV | Â | ||
|---|---|---|---|---|---|
| Â | BuCy | BuFlu | BuCy | BuFlu | P value |
Heart (single/multiple) | 4/8 | 2/4 | 2/0 | 0/0 | 0.048 |
Bladder | 5/8 | 2/4 | 0/1 | 0/0 | 0.010 |
Kidneys | 0/2 | 0/1 | 0/0 | 0/0 | 0.500 |
Lungs | 0/0 | 0/0 | 0/0 | 0/0 | Â |
Liver | 4/10 | 4/5 | 0/1 | 0/0 | 0.165 |
CNS | 0/0 | 0/1 | 0/3 | 0/0 | 0.618 |
Mucosa | 16/20 | 15/9 | 0/0 | 0/0 | 0.020 |
Gut | 1/24 | 10/6 | 0/2 | 0/0 | 0.018 |