TY - JOUR AU - Wun, Ted AU - Soulieres, Denis AU - Frelinger, Andrew L. AU - Krishnamurti, Lakshmanan AU - Novelli, Enrico M. AU - Kutlar, Abdullah AU - Ataga, Kenneth I. AU - Knupp, Charles L. AU - McMahon, Lillian E. AU - Strouse, John J. AU - Zhou, Chunmei AU - Heath, Lori E. AU - Nwachuku, Chuke E. AU - Jakubowski, Joseph A. AU - Riesmeyer, Jeffrey S. AU - Winters, Kenneth J. PY - 2013 DA - 2013/02/17 TI - A double-blind, randomized, multicenter phase 2 study of prasugrel versus placebo in adult patients with sickle cell disease JO - Journal of Hematology & Oncology SP - 17 VL - 6 IS - 1 AB - Platelet activation has been implicated in the pathogenesis of sickle cell disease (SCD) suggesting antiplatelet agents may be therapeutic. To evaluate the safety of prasugrel, a thienopyridine antiplatelet agent, in adult patients with SCD, we conducted a double-blind, randomized, placebo-controlled study. SN - 1756-8722 UR - https://doi.org/10.1186/1756-8722-6-17 DO - 10.1186/1756-8722-6-17 ID - Wun2013 ER -