Figure 1From: Inosine Triphosphate Pyrophosphohydrolase (ITPA) polymorphic sequence variants in adult hematological malignancy patients and possible association with mitochondrial DNA defectsOverview of purine metabolism and ITPase ‘futile cycle’. ITPase: Inosine triphosphate pyrophosphohydrolase; IMP: Inosine monophosphate; XMP: Xanthosine monophosphate; GMP: Guanosine monophosphate; dITP: deoxy-Inosine triphosphate; AMP: Adenosine monophosphate.Back to article page